First, make the following macro assumptions about the basic universe values (macro assumptions mean that if you don't agree that this is an axiom, then you don't have to continue to infer).
1.1 The second law of thermodynamics => the inevitable progress of the universe towards heat death (entropy increase).
1.2 The emergence of life and civilization is entropy reduction. The purpose of this entropy reduction is faster global entropy increase (it can be simply understood as the creation of atomic bombs by humans in order to make the universe "destroy" faster).
1.3 Evolution (Evolution is more appropriate, whether natural selection or thought selection) determines the rate at which this entropy of life decreases. Under the premise of ensuring the overall survival, the pursuit of a faster evolution speed is the instinctive trend of all life.
Going on, as a movie, I think it provides such a default setting.
2.1 There is an X area on the earth that can greatly accelerate the evolution, and this area cannot be destroyed by weapons that can be used by humans. (acceptable)
2.2 DNA is the basic code of life, which determines the hardware and even part of the software of life. (Basic consensus)
2.3 The hardware foundation of life can be upgraded online in real time. (As "Life 3.0" talks about future AI)
2.1 As mentioned in all things like "Roadside Picnic", there are many possibilities to have a huge impact on human civilization, and you don't need to worry about the reasons behind this.
3.1 With reference to 1.3, the "meaning" of life in human language is evolution. In layman's terms, "hold up" and "fall to death" faster.
3.2 According to 2.3, a direct inference can be drawn. Evolution can be carried out through "natural evolution" of reproduction + physical destruction, or through hardware OTA.
To sum up, "annihilation" presents a scene where human civilization 2.0 meets a "life 3.0". The story is simply that, human beings encounter a life 3.0 that can guarantee their own survival and can also absorb various external diversity (DNA). Without tens of thousands of years, hundreds of millions of years of natural selection, this Life 3.0 can allow various DNAs to compete efficiently in it. After quick screening, internal testing, and finding a lifeform suitable for the environment, this life 3.0 released a version and started the public test.
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