Ever since his fateful encounter with the three lovely little girls, Margo, Edith, and Agrace, the former villain Gruke has completely transformed. He washed his hands and turned into a kind and amiable father and a businessman who makes bad-tasting pudding jelly. Of course, nothing is perfect. During this period, Dr. Nafario, his old partner who longed for the legendary life of the big bad guy, left him and found another job. One day, Gru was kidnapped by a talented but reckless agent, Lucy Wilde. It turned out that Lucy's group had developed drugs that could change biological genes, but their laboratory in Antarctica was stolen by mysterious thieves, so they commissioned him. Gru, who has experience as a bad guy, goes undercover. After some deliberation, Gru accepted the task, brought the super cute minions, and formed a hilarious pursuit partnership with Lucy.
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