The conflict can be more profound, without affecting it as an excellent work

Bailee 2022-04-23 07:01:03

To Dallas Buyers Club

Regarding the subject matter, the most critical conflict in the film is that Matthew learned that he had HIV. The doctor told him that he had only a 30-day lifespan, and the FDA still did not have an approved anti-AIDS drug. AZT was directly put into clinical trials without animal experiments, and was pushed by the pharmaceutical factory , the attending doctor covered up part of the data, so Matthew started smuggling anti-AIDS drugs, and established the Dallas Buyer Club to provide non-compliant and plausible treatment for Aids patients.

In the film, AZT is directly masked, defined as the villain of the interest chain colluding with pharmaceutical companies and doctors. AZT, Azidothymidine, launched in 1987, the first anti-AIDS drug approved by the FDA, as a reverse transcriptase inhibitor, described in the 1987 NEJM RCT results These data demonstrate that AZT administration can decrease mortality and the frequency of opportunistic infections in a selected group of subjects with AIDS or AIDS–related complex, at least over the 8 to 24 weeks of observation in this study. (N Engl J Med 1987; 317:185–91.) The current mainstream anti-AIDS program, HAART, Lamy Vudine + tenofovir + efavirenz, also based on multi-target antiviral, the timing of treatment, the discovery is treatment. Another deified drug in the movie, (peptideT) T-peptide, what is it? T-peptide is a competitive inhibitor of gp120 glycoprotein binding to CD4 antigen. Use peptide T, HIV as keywords to search Pubmed, unfortunately, I did not search for high-profile journals like New England, and occasionally a few articles on the use of AIDS as an immune booster. Having said that, the point I want to express is that the conflict over the dark side of interests could have been stronger and fairer. Of course, little bugs don't make it an excellent movie.

About actors, acting skills, and sweeping the male lead and male supporting role has already explained everything, but, Leto, as a young master, that kind of melancholy temperament, that eyes, a frown and a smile, and that long legs, uh, I am a passerby. Matthew, I thought it was Uncle Bale, this kind of American uncle made me face blind, plus Jennifer Garner (haha, gossip a little, Big Ben's ex-wife) cast very much.

As for the idea, I don't like it, and it ended up falling into a cliché, a positive life; as for the shaping of the character, the director put a lot of effort, but more depends on the two excellent actors, the acting skills are really impeccable .

About the plot. . . I'm going to write my paper, forget it, I wrote this for the first time in 2018, put my dreams aside, and a sideline is king!

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Extended Reading
  • Angela 2021-10-20 19:00:05

    The pure story adapted from real events is really crazy about the performance of the hero and heroine!

  • Monte 2021-10-20 19:00:06

    A drug addict, a drug addict, and an AIDS patient at the same time completed a self-salvation in his own extreme way. From the beginning for profit, to later for rights, he gradually upgraded to a fighter, a fighter for justice and fairness for LGBT in the 1980s. Matthew McConaughey gave an Oscar-level performance. Whether he will win an award depends on whether the judges are afraid of sensitive topics.

Dallas Buyers Club quotes

  • Dr. Eve Saks: None of those drugs have been approved by the FDA.

    Ron Woodroof: Screw the FDA. I'm gonna be DOA.

  • Ron Woodroof: I don't want a nurse. I want a doctor. I want a goddamn doctor now!

    Dr. Eve Saks: Well, how can I help you?

    Ron Woodroof: You fucking deaf, lady? Hmm?

    Dr. Eve Saks: No, I'm a fucking doctor.