The super-cool heroine Alice (Milla Jovovich), a glamorous female freedom fighter, is
a scientific madman's experiment against the powerful Umbralle company and her own destiny.
I want to come to the game to have more philosophies and more interesting, but unfortunately I have not played the
following related backgrounds collected on the Internet:
What is a virus?
I am afraid that most people understand that viruses are: they can cause disease and are the smallest creatures (some people think they are not creatures). In fact, if we learn more, we can find more interesting things, which have a lot to do with the settings in the game. To be honest, viruses are really attractive things. If I were a relevant professional, I would not be able to resist the idea of creating or modifying viruses, so please forgive the scientists at Umbrella.
The core part of the virus is a small amount of genetic material, that is, a chromosome composed of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), surrounded by a protein shell. Because it does not have a cellular structure, it has a small body and is immune to antibiotics.
Usually when a virus infects a victim cell, it first attaches to the cell surface, uses enzymes to dissolve a small hole on the cell surface, and then injects its own genetic material into the cell, which is connected to the genetic material in the cell nucleus through transcription (usually composed of a large section). DNA is connected into a set of chromosomes, such as humans have 23 pairs of chromosomes). Since an enzyme can only dissolve specific types of proteins, the types of organisms that a virus can infect are also very limited.
Viruses are divided into virulent viruses (also called virulent viruses) and mild viruses, and the process after infecting cells is different.
If it is a potent virus, it will break the cell chromosomes and become the material for the synthesis of virus chromosomes. The synthesized viral chromosomes will control the synthesis of new viral protein coats, which are then assembled into new viruses. Finally, the cell disintegrates and releases a large number of progeny viruses.
If it is a mild virus, the method is more "mild." Mild viruses only occasionally perform the above-mentioned virulent virus behavior, and in most cases undergo a process called the lysogenic cycle. In this process, the virus parasitizes in the cell relatively stably, the cell will continue to live and proliferate, and sometimes release a small amount of virus. This kind of cell that survives infection by a mild virus is called a lysogen. The lysogen is immune to the same virus that has been infected, and when dividing, it will pass this lysogenicity to the offspring cells (that is, offspring). Cells also integrate the same virus), without intervention, the lysogenicity can be passed on almost semi-permanently.
So what kind of virus is T virus?
We have not seen the vitality failure caused by the massive lysis of the biogenic cells infected with the T virus. In fact, the biological weapons developed are quite stable, and the zombies have better physical strength than normal people. If it is a severe virus infection, although eating can make up for the loss to a certain extent, because the virus grows in a geometric progression, the rate of damage to organisms will become faster and faster, until the biological metabolism cannot catch up and eventually lead to death. So we can rule out the virulent virus.
Then the T virus is a mild virus. It will live in symbiosis with the host. As mentioned above, the types of organisms that a virus can infect are very limited, and there are many types of organisms that are victimized in the game, so T virus should be the general term for a type of virus with the same function.
What is the use of T virus?
Although we have seen the terrifying army of zombies in Raccoon City, the original purpose of Umbrella's research on T virus is not to create zombies, nor to directly spread T virus, but to use T virus to develop biological weapons (BOW). These biological weapons include Cerberus (Cerberus, only refers to a generation of dogs), Neptune (Neptune, a generation of sharks), Hunter (Hunter), Tyrant (Tyrant, including the parasite Nemesis pursuers), and walking plants (Ivy) and many more.
Why use viruses to develop biological weapons? In fact, the core part of these development projects is genetic recombination. This is not about regrouping chromosomes like hybridization, but about changing the chromosomes themselves. In contrast, the cloning technology, which was so heated at the end of the 20th century, was actually just an introductory technique.
As mentioned earlier, mild viruses will integrate their genetic material into the chromosomes of the host cell and coexist for a long time. During this symbiosis period, it is obvious that the genotype of the host cell is changed due to the integration of the virus chromosome, and the cell's traits will also change accordingly (this is called lysogenic conversion). This means that the host itself will mutate more or less, and may even mutate into another organism, depending on the size and nature of the impact of this integrated virus (referred to as provirus or provirus) on the host. We can see the result directly in the game: the impact of the T virus is huge, and its change in the direction of biology is exactly what researchers need. The various biological weapons that have been successfully developed in the laboratory have generally met expectations.
Why do citizens infected with T virus show symptoms of decay, high appetite, and lethargy?
Both rot and bulimia are due to the same reason: T virus infection is blocked by the body's immune system. Immune cells will try to kill the infected cells, and they usually use the "together" approach, which leads to a large number of necrotic tissues in the body. In order to repair the loss of tissues and restore the function of the immune system, a large amount of food is needed to provide materials and energy sources, which makes the infected person have a strong appetite.
As for drowsiness, it can only be considered as the result of brain infection. Although it is impossible to figure out the details, we only need to know that this is not normal.
It should be noted that under normal circumstances, the brain is isolated and protected by a tissue called the "blood-brain barrier" and does not touch immune cells. Therefore, if the barrier is not damaged, the brain is hopeful that it will mutate relatively well. Therefore, zombies can still walk upright and have foraging behavior. (Antibodies can enter the brain, but antibodies do not damage cells. This is just a side note. If you are interested, you can check the keywords "cellular immunity" and "humoral immunity".)
The biological weapons cultivated by Umbrella should be from fertilized eggs ( (Or early embryo) period is changed with T virus, so it can avoid the interference of the immune system and the drag of the growth condition before infection, and obtain a healthy and stable mutant organism. Obviously, the fertilized eggs are not limited to one kind of organism, and foreign genes can be mixed as needed, which makes biological weapons more diverse.
Why does the length of time for the victim to become a zombie vary?
Everyone's physique is different. For a strong healthy person, it is a difficult process for a small virus that occasionally touches the skin to defeat the immune system, and it may even be completely wiped out. Before the Raccoon crisis broke out, most of the first victims were only in the sewers. Contact with small organisms carrying the virus, and in good health, can still maintain normal for several days, during this period symptoms such as itching (minor tissue necrosis), bulimia, etc. appear. A person who is attacked by a zombie to the point of death is different. His immunity is so weak that the virus can easily invade, and if the virus enters the blood directly from the wound, it will spread to all parts of the body in a very short time. Greatly accelerate the infection process.
The large-scale spread or outbreak of the virus in Raccoon City was mainly caused by zombie attacks. Assuming that a zombie attacks two people every two hours on average, and the victim becomes a zombie in two hours on average, then from the first zombie, there will be 3 zombies in two hours, and 9 in four hours,...20 Four hours later, there will be 531,441. Raccoon has a population of only 100,000.
G virus
What kind of virus is G virus? What is the difference between G virus and T virus?
G virus is still mild virus like T virus. Of course, the mutant creatures they produce are different. This is what everyone has seen, but this is not the most important thing.
As mentioned earlier, T virus-infected adult organisms are unstable and relatively low-capacity. Only after the fertilized egg is infected can it grow into a healthy mutant organism. The G virus has different functions and can be used for adult organisms. This is the unique feature of William Birkin's research results. In Biochemistry II, we also saw William's personal experience.
His wife Annette has this line: "(G virus) is very different from T virus, which can only make waste zombies." Why do you compare G monsters with zombies? Didn't T virus also create products that are no less inferior to G monsters like tyrants? The reason is that tyrants and other T-type biological weapons can only be cultivated from fertilized eggs, and G monsters, like zombies, are mutations generated from biological adults, and are incomparable with T-type biological weapons.
It is worth mentioning that Wesker also achieved adult mutation through the virus provided by William Birkin. This virus is obviously similar to G virus or a certain type of G virus, and Wesker's eyes are a hint.
So how does the G virus solve the immune problem of adult organisms?
The easiest thing to think of is that the G virus may be able to completely control the immune organs in a short time, but based on the clues in the game, I think the greater possibility is that the immune system cannot recognize the G virus and the infected cells. I don’t have a clear answer as to how the G virus does this. But there is no shortage of similar examples in reality, such as tumors.
But we know that even if they are both humans, the transplanted organs are likely to be rejected by the immune system as foreign bodies. Therefore, the G virus that can disguise the substance of host A may not be able to disguise itself as the substance of host B. Therefore, it is likely that the G virus must be customized for the designated host individual. William customized the G virus for himself in the experiment. The original intention is unknown, but it was really used later.
This can also explain why the G virus injection tube destroyed by William after his transformation did not cause a large number of G monsters to appear in Raccoon, because there are few people who are sufficiently compatible with William's genotype. Ordinary people who come into contact with the G virus may produce zombie-like mutations, or they may not be infected at all. It depends on how William designed the G virus.
Personally, I suspect that Licker (Licker) is a mutation of ordinary people infected with G virus. This kind of monster has only appeared in Raccoon City, and only in the biochemical 2 and biochemical network versions that involve more G viruses, and stronger individuals appear in William's factory. However, this speculation still lacks a direct basis.
But G larvae can still parasitize other creatures and grow into G monsters, because it is not a virus, but a biological embryo.
G larvae are produced from G monsters and are forcibly implanted into other organisms by G monsters. Its metabolism in the host is similar to that of malignant tumors, but there are also differences from tumors. A tumor can become a tumor after it escapes the surveillance of the immune system. This is one of the prerequisites for it to develop from a mutant cell into a tumor. After the G larvae parasitizes a strange creature, the conditions for avoiding surveillance and avoiding rejection are similar to those of the G virus. In other words, unless the host is sufficiently similar to William's genotype, it is almost inevitable that G larvae will be rejected.
The result of rejection is that G larvae will tear open the host body to escape once they have grown to be able to escape, because the host's immune system is not enough to eliminate or even contain the very vigorous G larvae, but it will definitely make it painful. That's why the director Brian Irons or reporter Ben Bertolucci died tragically shortly after being parasitized.
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