- There did exist a magazine called "MODE", which targeted women in oversized clothing. The magazine ceased publication in 2001.
- Although the story of "Ugly Betty" took place in New York and the first episode was filmed in New York, the rest of the show was filmed in Los Angeles. Like other TV series, "Betty" often inserts some material clips of New York scenery to confuse the audience.
- Patricia Field (the costume designer for "Sex and the City" and "The Devil in Prada") took over all the costume designs for the first episode of the show. After "Ugly Betty" moved to Los Angeles, she left the crew who lived in New York.
- The letter "B" pearl necklace worn by Betty is an imitation of the famous necklace once worn by Henry VIII's second wife and Elizabeth I's mother Anne Bolin.
- On Betty's bedside table is a book called "The Sisterhood of the Traveling Pants" (The Sisterhood of the Traveling Pants). America Georgine Ferrera once played the role of Carmen in the film of the same name based on this book.
- Silvio Horta, the creator of "Ugly Betty", is a public gay who once said that he saw his childhood in Justin.
- The scene of the exterior of the exhibition at the Museum of Modern Art in New York was actually shot at the New England Aquarium in Boston, and CG technology was used to process the scenes in post-production.
- In the episode of "FakePlasticSnow", Mark's full name is Mark Saint-James (MarkSaint-James), but in the episode of "Don't Ask Don't Tell", his full name becomes Mark Weiner (Mark Weiner) .
- Although the French fashion channel FashionTV has been mentioned many times in the show, there is no connection between the two.
- "Ugly Betty" was a huge success after it was broadcast in the United States, and many people drew inspiration from Halloween costumes.
- "Ugly Betty" also has an Indian relative, "JassiJaissiKoiNahin", which is also based on the Colombian version. The play is very popular in the local area and occupies the prime time of the TV station. Betty is earlier than the American version of Betty.
- America Georgine Ferrera had to make up for 45 minutes in each episode in order to be ugly.
Ugly Betty behind the scenes gags
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Betty Suarez: [Betty wants to set up Daniel with another celebrity] Somebody like Jennifer Aniston would be amazing.
Christina McKinney: Betty, fixing up Daniel isn't part of your job description, is it?
Betty Suarez: I know, I know, I just feel so guilty. What about Tara Reid?
Christina McKinney: Lovely. Dinner with Tara Reid, breakfast at the free clinic.
Betty Suarez: Right. Oh, Gisele! I wish I could make that happen, Gisele would make Daniel forget about Sofia.
Christina McKinney: So do it.
Betty Suarez: What do you mean, "So do it"? It's Gisele, it's not like we go to the same laundromat.
Christina McKinney: Don't be such a numpty. You phone her representative and you arrange a dinner date.
Betty Suarez: Celebrities do that?
Christina McKinney: Where do you think Tom and Katie hooked up? Church?
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Christina McKinney: Oh, the sound of clinking ice cubes. It's like a Scottish lullaby.