The sex worker he found was Cheryl Cohen Green, a woman who had been in sex work for some years. After having sex with O'Brien and getting paid, he left O'Brien and never had any contact with him again. O'Brien wrote about his sexual experience in his article "Experiential Therapy" and published it in the 1990 issue of "The Sun Magazine". Later, Mark O'Brien published his biography, "How I Became Human: People with Disabilities Seek Independence". In addition to describing the daily life of Mark O'Brien, this book also introduces his views on life, life and the meaning of life in detail. The "breakthrough experience" of searching for sex workers has also become a milestone in Mark O'Brien's transformation from a boy to a man, seeking the meaning of life. In 1996, Chinese filmmaker Yu Linmin filmed a documentary "Marc O'Brien's Life and Work" for O'Brien, which recorded the story of O'Brien working and living with a ventilator, and she was still in the film Discussed the sexual life of people with disabilities and so on. This documentary short film received a lot of applause as soon as it was released, especially O'Brien's jokes about his body in the film, and his optimistic and positive spirit has infected many people. At the 1997 Oscar, the film won the Oscar for Best Documentary Short Film.
After this movie, O'Brien has almost become a role model for Americans with disabilities, especially his optimistic attitude towards life and ignoring physical obstacles, has become the most American-styled role model for a period of time. Three years later, in 1999, O'Brien died at the age of 49 due to long-term physical weakness.