"Piranha 3D" was set in Victoria Nyanza , Arizona , USA . The beautiful lake water is refreshing, but the local female police officer Julie Forrest and colleagues discovered the cause of Matt's death when investigating the disappearance of the fisherman Matt. Strange, then more and more people disappeared strangely. At this time, the U.S. Geological Survey detected a strong earthquake at the bottom of the lake. The monitors Novak and Sam dived into the bottom of the lake to investigate the situation. Unfortunately, they were torn to pieces by piranhas. After verifying that the police officer Julie knew the seriousness of the matter, At this time, people from all directions are on vacation in Victoria Nyanza.
In order to minimize the damage as much as possible, police officer Julie Forrest and others came to the lake to stop young men and women who were swimming in the water, but they did not listen and did not return to the shore as required by the police. As a result, piranhas attacked in groups, killing a large group of people. At this time, at the invitation of TV personality Derek Jones, the young Jack Foster followed his friends to the beach. Jack and his favorite girl, Kelly, and other friends boarded Derek’s yacht and sat on the sightseeing boat together. They were playing in the lake, but their boat hit the rocks. Derek fell into the water and was killed by a piranha. Jack was also trapped. At this time, he called his mother for help, and his mother Julie and the police quickly rushed to rescue them.