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The filming took 94 days.
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The crew initially hoped to film scenes of human and elephant fighting in India, but the elephants in India lacked good training, so they had to switch to Thailand.
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Colin Farrell broke his arm and injured his ankle during filming.
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Val Kilmer gained 50 pounds for the film, and it took 1 hour to put on makeup every day.
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Brad Pitt was the original candidate to play, but he refused because of concerns about the role.
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The first person to play Philip was Sean Connery.
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Heath Ledger was also considered to play Alexander the Great.
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The accent of the Macedonian soldiers in the film does not match that of the Greeks, because historically these Macedonians came from remote hill tribes, so they have a Celtic accent in the film, which is of course similar to that of Aristotle and other fine Greeks. People's British accents are very different, but many people don't understand that this is a deliberate design.
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In the Battle of Gaugamela, the Persian army wore black uniforms, but in fact it should be yellow and light purple.
Alexander behind the scenes gags
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Olympias: Three months you have been in Babylon, and leave me at the mercy of your enemies, of which you have many. Antipater: accustomed now to the power that you have given him. I must watch him grow stronger. I am certain that he communicates secretly with Parmenion, who is dangerous. But beware most of all of those closest to you. They are like snakes, and can be turned. Cassander is Antipater's son. Even Cleitus, your father's favorite. And Ptolmey. Your friend, yes, but beware of men who think too much. They blind themselves. Only Hephastion do I leave out. But all of them you make rich, while your mother and yourself you leave in generous poverty. Why won't you ever believe me? It is only a dark mind like mine that can know these secrets of the heart. For they are dark, Alexander. So dark. But in you, the son of Zeus, lies the light of the world. Your companions will be shadows in the underworld when you are a name living forever in history as the most glorious, shining light of youth. Forever young, forever inspiring. Never will there be an Alexander like you, Alexander the Great.
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Philip: [to Young Alexander] A king isn't born, Alexander, he is made. By steel and by suffering. A king must know how to hurt those he loves. It's lonely. Ask anyone. Ask Heracles. Ask any of them. Fate is cruel. No man or woman can be too powerful or too beautiful without disaster befalling. They laugh when you rise too high. And they crush everything you've built with a whim. What glory they give in the end, they take away. They make of us slaves.